Description
Key information
- Concentration : Each 1 mL vial contains 20 mg of hydralazine hydrochloride.
- Administration : This medicine is given by a healthcare professional by intramuscular (IM) or slow intravenous (IV) injection.
- Indications : It is used to manage hypertensive emergencies, especially when the oral route is contraindicated, and often for high blood pressure associated with preeclampsia or eclampsia during pregnancy.
- Mechanism of action : Hydralazine acts as a direct arterial vasodilator, relaxing the blood vessels and lowering blood pressure.
- Directions : This medicine is usually intended for urgent, short-term use in hospital, after which patients are usually switched to oral treatment within 24 to 48 hours.
Important notes
- Dilution : The solution can be diluted with 0.9% sodium chloride solution for slow intravenous injection. Once the vial is opened or diluted, any unused portion must be discarded immediately. Adverse effects: Common adverse effects may include headache, nausea, palpitations and a faster heart rate (tachycardia).
- Contraindications : This medicine is contraindicated in patients with known hypersensitivity to hydralazine, coronary artery disease or rheumatic mitral valve disease.
- Monitoring : Blood pressure and heart rate must be monitored frequently during and after administration to prevent an excessive drop in blood pressure or other adverse effects.
