Description
Key information
- Active ingredient : Tramadol hydrochloride.
- Manufacturer : Denk Pharma, a German pharmaceutical laboratory.
- Indication : Treatment of moderate to severe pain, such as post-operative or cancer pain, in patients over 12 years old.
- Method of administration : Given intravenously (slow injection or infusion), intramuscularly or subcutaneously, usually in a hospital setting.
- Dosage : The dose is adjusted to the intensity of the pain and the patient’s individual sensitivity, and must always be the lowest effective dose. The usual adult dosage is 50 to 100 mg every 4 to 6 hours (maximum 600 mg per day).
- Mechanism of action : Tramadol works by binding to opioid receptors in the central nervous system and by inhibiting the reuptake of noradrenaline and serotonin, which changes how the brain and body perceive and respond to pain.
Important considerations :
- This medicine must only be used under medical supervision and for the strictly necessary duration because of the risk of dependence and other serious adverse effects.
- Common adverse effects include nausea, dizziness, constipation, headache and drowsiness.
- It is contraindicated in acute alcohol intoxication, in combination with certain medicines (such as MAOIs), and in patients with severe liver failure or uncontrolled epilepsy.
- Always consult a healthcare professional for specific information on use, dosage and potential adverse effects. More detailed product information is available on the Denk Pharma website or on regulatory sites such as the eMC.
